https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27497 Wed 31 Jul 2019 09:42:43 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48709 Wed 29 Mar 2023 17:26:24 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45282 Wed 26 Oct 2022 20:12:03 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45141 Wed 26 Oct 2022 13:40:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30810 Wed 23 Feb 2022 16:04:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31015 Wed 17 Nov 2021 16:28:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22520 Wed 11 Apr 2018 17:20:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12931 Wed 11 Apr 2018 17:11:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13782 Wed 11 Apr 2018 16:59:23 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22846 Wed 11 Apr 2018 16:46:51 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9716 Wed 11 Apr 2018 16:28:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12426 Wed 11 Apr 2018 16:10:55 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7507 Wed 11 Apr 2018 16:09:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20669 Wed 11 Apr 2018 15:57:11 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24185 Wed 11 Apr 2018 15:51:51 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13569 Wed 11 Apr 2018 15:29:46 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15677 Wed 11 Apr 2018 15:24:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20024 Wed 11 Apr 2018 15:18:06 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22740 amount of information provided' (median score=5, "just right"), all aspects of training attained the most positive score of '1'. Pharmacists most valued the integrated team-based approach, GP involvement, and inclusion of real patients, as well as the pre-reading manual, BP measurement workshop, and case studies (simulation). Post-implementation the interviews highlighted that comprehensive training increased pharmacists' confidence in providing the service, however, training of other pharmacy staff and patient recruitment strategies were highlighted as a need in future. Conclusions: Structured, multi-modal training involving simulated and inter-professional learning is effective in preparing selected community pharmacists for the implementation of new services in the context of hypertension management. This training could be further enhanced to prepare pharmacists for the challenges encountered in implementing and evaluating services in practice.]]> Wed 11 Apr 2018 15:01:06 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7264 Wed 11 Apr 2018 14:42:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15676 Wed 11 Apr 2018 14:24:58 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9928 Wed 11 Apr 2018 14:11:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15463 Wed 11 Apr 2018 13:43:44 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14828 Wed 11 Apr 2018 13:41:35 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18256 Wed 11 Apr 2018 13:33:57 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16208 Wed 11 Apr 2018 13:33:56 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15312 Wed 11 Apr 2018 13:14:59 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23011 Wed 11 Apr 2018 12:35:32 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24184 Wed 11 Apr 2018 12:25:08 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27949 Wed 11 Apr 2018 12:00:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13895 Wed 11 Apr 2018 11:47:28 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4362 Wed 11 Apr 2018 11:36:43 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13533 21 on the Kessler 10) were examined using logistic regression. Results: Not being in a married or defacto relationship (OR 0.69; 99% CI 0.51-0.94), lower education (OR 0.52; 99% CI 0.38-0.71) and decreased social support (OR 0.36; 99% CI 0.31-0.42) significantly predicted psychological distress. There was a significant interaction of age and remoteness (OR 0.84; 99% CI 0.67-1.00), indicating that as remoteness increases, older persons are less likely to be highly distressed, as well as a significant interaction of social support and remoteness (OR 1.22; 99% CI 1.04-1.44), indicating that as remoteness decreases, persons with low levels of social support are more likely to be highly distressed. Conclusions: Remoteness may moderate the influence of social support and age on psychological distress outcomes.]]> Wed 11 Apr 2018 11:23:50 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16786 Wed 11 Apr 2018 11:23:35 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:6817 Wed 11 Apr 2018 11:09:23 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29993 n = 46) had fewer than 10 clusters. Of the 42 articles discussing the design methodology 10 covered analysis and seven covered sample size. For cohort stepped wedge designs there was only one paper considering analysis and one considering sample size methods. Most trials employed either a GEE or mixed model approach to analysis (n = 77) but only 22 trials (22 %) estimated sample size in a way which accounted for the stepped wedge design that was subsequently used. Conclusions: Many studies which employ the stepped wedge design have few clusters but use methods of analysis which may require more clusters for unbiased and efficient intervention effect estimates. There is the need for research on the minimum number of clusters required for both types of stepped wedge design. Researchers should distinguish in the sample size calculation between cohort and cross sectional stepped wedge designs. Further research is needed on the effect of adjusting for the potential confounding of time on the study power.]]> Wed 11 Apr 2018 11:00:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15681 Wed 11 Apr 2018 10:51:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:6851 Wed 11 Apr 2018 10:50:17 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26702 Wed 11 Apr 2018 10:47:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4378 A, causes overexpression and supports uncontrollable cellular growth. This polymorphism has been associated with an increased risk of developing many cancers, including endometrial cancer. Methods: The 870 G>A polymorphisms (rs605965) in the cyclin D1 gene was genotyped in an Australian endometrial cancer case-control population including 191 cases and 291 controls using real-time PCR analysis. Genotype analysis was performed using chi-squared (χ²) statistics and odds ratios were calculated using unconditional logistic regression, adjusting for potential endometrial cancer risk factors. Results: Women homozygous for the variant cyclin D1 870 AA genotype showed a trend for an increased risk of developing endometrial cancer compared to those with the wild-type GG genotype, however this result was not statistically significant (OR 1.692 95% CI (0.939-3.049), p = 0.080). Moreover, the 870 G>A polymorphism was significantly associated with family history of colorectal cancer. Endometrial cancer patients with the homozygous variant AA genotype had a higher frequency of family members with colorectal cancer in comparison to endometrial cancer patients with the GG and combination of GG and GA genotypes (GG versus AA; OR 2.951, 95% CI (1.026-8.491), p = 0.045, and GG+GA versus AA; OR 2.265, 95% CI (1.048-4.894), p = 0.038, respectively). Conclusion: These results suggest that the cyclin D1 870 G>A polymorphism is possibly involved in the development of endometrial cancer. A more complex relationship was observed between this polymorphism and familial colorectal cancer.]]> Wed 11 Apr 2018 10:44:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26853 Wed 11 Apr 2018 10:14:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7526 Wed 11 Apr 2018 10:11:50 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13911 Wed 11 Apr 2018 10:01:39 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25317 Wed 11 Apr 2018 10:00:24 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:75 Wed 11 Apr 2018 09:52:45 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22815 Wed 11 Apr 2018 09:51:58 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20498 30 years old) after performing a multi-stage random selection procedure. We administered a questionnaire, and collected fasting serum samples and urine samples. We used the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation to estimate glomerular filtration rate, and sex-specific cut offs for albuminuria: > 1.9 mg/mmol (17 mg/g) for men, and >2.8 mg/mmol (25 mg/g) for women. We assessed health-related quality of life using the Medical Outcomes Study Short Form-12 (SF-12). Results: A total of 357 (89%) participants with serum samples comprised the analytic cohort. Mean age of was 49.5 (± 12.7) years. Chronic kidney disease was evident in 94 (26%). Of the participants with CKD, 58 (62%) had albuminuria only. A participant with insulin resistance had a 3.6-fold increase in odds of CKD (95% confidence interval 2.1 to 6.4). Participants with stage three or more advanced CKD reported a decrement in the Physical Health Composite score of the SF-12, compared with participants without CKD. Conclusion: We found an alarmingly high prevalence of CKD—particularly CKD associated with insulin resistance—in middle-income, urban Bangladeshis.]]> Wed 11 Apr 2018 09:50:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14832 Wed 11 Apr 2018 09:49:46 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16781 out). The CSF infusion studies measuring R_out are dependent on venous sinus pressure but little is known about the changes in pressure which occur throughout life or with the development of hydrocephalus. Methods: Twenty patients with chronic hydrocephalus underwent MR venography and MR flow quantification techniques. The venous outflow pressure was estimated from the sinus blood flow and the cross-sectional area of the transverse sinuses. Adult controls as well as a normal young cohort were selected to estimate the change in sinus pressure which occurs throughout life and following the development of hydrocephalus. Significance was tested with a Student’s t-test. Results: The size of the transverse sinuses was unchanged from the 1^st to the 5^th decade of life, indicating a stable outflow resistance. However, the blood flow was reduced by 42%, indicating a likely similar reduction in pressure gradient across the sinuses. The sinuses of hydrocephalus patients were 38% smaller than matched controls, indicating a 2.5 times increase in resistance. Despite the 24% reduction in blood flow, a significant increase in sinus pressure is suggested. Conclusions: The size of the venous sinuses normally does not change over the age range investigated but sinus pressure is reduced proportional to an age-related blood flow reduction. Hydrocephalus is associated with much smaller sinuses than normal and an elevation in venous pressure may explain the lack of CSF absorption into the arachnoid granulations in chronic hydrocephalus.]]> Wed 11 Apr 2018 09:46:05 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9714 Wed 11 Apr 2018 09:43:06 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17559 Wed 11 Apr 2018 09:42:10 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16767 Wed 11 Apr 2018 09:38:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29080 n = 38). Inductive, thematic analysis was conducted using framework data management methods in NVivo10. Results: Five high-level themes were derived: the battle to access housing; secondary homelessness; overcrowding; poor dwelling conditions; and housing as a key determinant of health. Participants associated their challenging housing experiences with poor physical health and poor social and emotional wellbeing. Housing issues were said to affect people differently across the life course; participants expressed particular concern that poor housing was harming the health and developmental trajectories of many urban Aboriginal children. Conclusions: Housing was perceived as a pivotal determinant of health and wellbeing that either facilitates or hinders prospects for full and healthy lives. Many of the specific health concerns participants attributed to poor housing echo existing epidemiological research findings. These findings suggest that housing may be a key intervention point for improving the health of urban Aboriginal Australians.]]> Wed 11 Apr 2018 09:28:16 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13741 Wed 11 Apr 2018 09:24:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9231 Wed 11 Apr 2018 09:21:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31235 HI monocytes/macrophages and neutrophils. Body weight and clinical scores were recorded throughout the experiment. Results: We demonstrate that KB treatment attenuated cigarette smoke-induced lung inflammation as shown by reductions in levels of BAL IFNγ, CXCL9, CXCL10, CCL5, IL-6, G-CSF, and IL-17. KB additionally attenuated the quantity of BAL lymphocytes and macrophages. In parallel to the attenuation of lung inflammation, KB induced a systemic immune activation with increases in Ly6C^HI monocytes/macrophages and neutrophils. Conclusions: This is the first demonstration that subcutaneous administration of a microbial-based immunotherapy can attenuate cigarette smoke-induced lung inflammation, and modulate BAL lymphocyte and macrophage levels, while inducing a systemic immune activation and mobilization. These data provide a foundation for future studies exploring how KB may be used to either reverse or prevent progression of established emphysema and small airways disease associated with chronic cigarette smoke exposure. The data suggest the intriguing possibility that KB, which stimulates rather than suppresses systemic immune responses, might be a novel means by which the course of COPD pathogenesis may be altered.]]> Wed 10 Nov 2021 15:05:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45101 Wed 07 Feb 2024 17:04:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54615 Wed 06 Mar 2024 10:45:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34570 Wed 04 Sep 2019 09:48:31 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32816 Wed 02 Mar 2022 14:28:29 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49753 Tue 30 May 2023 17:21:57 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52730 Tue 24 Oct 2023 10:39:46 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24538 Tue 24 Aug 2021 14:23:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53963 Tue 23 Jan 2024 12:39:20 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37265 Tue 15 Sep 2020 13:05:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37944 Tue 11 Oct 2022 17:29:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35837 Tue 10 Dec 2019 17:09:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36391 Tue 07 Apr 2020 15:11:35 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33855 Tue 03 Sep 2019 18:30:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33960 Tue 03 Sep 2019 18:23:27 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26056 Thu 28 Oct 2021 12:37:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30240 EIG121) has been associated with breast and endometrial cancers, but its mechanism of action remains unknown. In a genome-wide search for tandem repeats, we found that EIG121 contains a short tandem repeat (STR) in its upstream regulatory region which has the potential to alter gene expression. The presence of this STR has not previously been analysed in relation to breast or endometrial cancer risk. Results: In this study, the lengths of this STR were determined by PCR, fragment analysis and sequencing using DNA from 223 breast cancer patients, 204 endometrial cancer patients and 220 healthy controls to determine if they were associated with the risk of developing breast or endometrial cancer. We found this repeat to be highly variable with the number of copies of the AG motif ranging from 27 to 72 and having a bimodal distribution. No statistically significant association was identified between the length of this STR and the risk of developing breast or endometrial cancer or age at diagnosis. Conclusions: The STR in the upstream regulatory region of EIG121 is highly polymorphic, but is not associated with the risk of developing breast or endometrial cancer in the cohorts analysed here. While this polymorphic STR in the regulatory region of EIG121 appears to have no impact on the risk of developing breast or endometrial cancer, its association with disease recurrence or overall survival remains to be determined.]]> Thu 28 Oct 2021 12:35:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45078  5 (high) among 353 pregnant women in the Kintampo North Municipality and Kintampo South District located within the middle belt of Ghana. We employed linear regression to determine associations between prenatal maternal stress and infant birth weight, head circumference, and length. We additionally examined associations between prenatal maternal stress and adverse birth outcome, including low birth weight, small for gestational age, or stillbirth. Effect modification by infant sex was examined. Results: In all children, high prenatal maternal stress was associated with reduced birth length (β = − 0.91, p = 0.04; p-value for trend = 0.04). Among girls, moderate and high prenatal maternal stress was associated with reduced birth weight (β = − 0.16, p = 0.02; β = − 0.18, p = 0.04 respectively; p-value for trend = 0.04) and head circumference (β = − 0.66, p = 0.05; β = − 1.02, p = 0.01 respectively; p-value for trend = 0.01). In girls, high prenatal stress increased odds of any adverse birth outcome (OR 2.41, 95% CI 1.01-5.75; p for interaction = 0.04). Sex-specific analyses did not demonstrate significant effects in boys. Conclusions: All infants, but especially girls, were vulnerable to effects of prenatal maternal stress on birth outcomes. Understanding risk factors for impaired fetal growth may help develop preventative public health strategies.]]> Thu 27 Oct 2022 12:20:33 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32829 Experiencing shame and stigma, and Reactive affect. The third theme addressed the coping resources of these informants under the theme: Surviving the stress of attempt. The specific coping resources included personalized spiritual coping, social support, and avoidance. Conclusions: Family systems theory is used to explain some of the findings of this study, and the implication for clinical practice and designing postvention programs for families after a suicide attempt are addressed.]]> Thu 24 Mar 2022 11:31:03 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29470 Thu 21 Oct 2021 12:51:57 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30806 Thu 14 Apr 2022 10:58:38 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37119 Thu 14 Apr 2022 10:58:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25771 Thu 13 Aug 2020 08:45:23 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50895 Thu 10 Aug 2023 10:29:50 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34996 Thu 04 Nov 2021 10:40:08 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27012 Thu 04 Nov 2021 10:39:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32792 Mon 23 Sep 2019 13:00:21 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32026 Mon 23 Sep 2019 11:59:16 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32775 Mon 23 Sep 2019 10:47:46 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32334 Mon 23 Sep 2019 10:19:48 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36290 Mon 23 Mar 2020 12:58:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53038 Mon 13 Nov 2023 09:02:15 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43018 Mon 12 Sep 2022 09:36:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54727 Mon 11 Mar 2024 14:11:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20880 Mon 11 Mar 2019 12:15:55 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30269 Mon 11 Mar 2019 12:09:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30630 1H-MRS) and localization techniques principles, different fast MRSI techniques will be discussed from their initial development to the recent innovations with particular emphasis on their capacity to record neurochemical changes in the brain in a variety of pathologies. The clinical applications of whole brain fast spectroscopic techniques, can assist in the assessment of neurochemical changes in the human brain and help in understanding the roles they play in disease. To give a good example of the utilities of these techniques in clinical context, MRSI application in multiple sclerosis was chosen. The available up to date and relevant literature is discussed and an outline of future research is presented.]]> Mon 11 Mar 2019 12:08:59 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30993 Mon 09 Oct 2023 14:50:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38402 Mon 06 Sep 2021 16:41:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45474 Fri 28 Oct 2022 14:37:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31131 Fri 22 Apr 2022 10:19:23 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40583 Fri 15 Jul 2022 10:46:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44513 Fri 14 Oct 2022 09:53:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44096 p < 0.001). After adjustment, there was no significant difference in referral to radiation oncology (intervention 32% vs control 30%; adjusted RR=1.06; 95% CI [0.74 to 1.51]; p=0.879). Sites with the largest relative increases in the percentage of patients discussed also tended to have greater increases in referral (p=0.001). In the intervention phase, urologists failed to provide referrals to more than half of patients whom the MDT had recommended for referral (78 of 140; 56%). Conclusions: The intervention resulted in significantly more patients being discussed by a MDT. However, the recommendations from MDTs were not uniformly recorded or followed. Although practice varied markedly between MDTs, the intervention did not result in a significant overall change in referral rates, probably reflecting a lack of change in urologists' attitudes. Our results suggest that interventions focused on structures and processes that enable health system-level change, rather than those focused on individual-level change, are likely to have the greatest effect.]]> Fri 07 Oct 2022 08:50:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51363 Fri 01 Sep 2023 13:43:43 AEST ]]>